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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNNI3K
All Species:
6.06
Human Site:
S925
Identified Species:
13.33
UniProt:
Q59H18
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q59H18
NP_001106279.1
936
104179
S925
M
S
S
M
H
F
H
S
C
R
N
S
S
S
F
Chimpanzee
Pan troglodytes
XP_513493
949
105567
S938
M
S
P
M
H
F
H
S
C
R
N
S
S
S
F
Rhesus Macaque
Macaca mulatta
XP_001097254
949
105560
F938
M
S
P
M
H
F
H
F
C
R
N
S
S
S
F
Dog
Lupus familis
XP_537112
1087
119299
V1076
R
G
L
Q
S
S
P
V
D
K
Y
G
E
Y
T
Cat
Felis silvestris
Mouse
Mus musculus
Q5GIG6
834
92569
R824
S
P
M
H
L
H
S
R
R
N
S
G
S
F
E
Rat
Rattus norvegicus
Q7TQP6
835
92713
R825
S
L
T
H
L
H
S
R
Q
D
D
S
N
F
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001339957
835
92821
C825
S
T
M
R
F
H
S
C
S
S
N
G
S
F
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001021182
850
93167
I840
V
E
E
L
R
Q
R
I
D
N
N
G
Y
V
I
Sea Urchin
Strong. purpuratus
XP_782227
862
95496
V852
D
P
L
S
T
L
R
V
N
D
S
P
I
L
P
Poplar Tree
Populus trichocarpa
XP_002336079
539
60951
K529
R
M
V
C
E
G
S
K
I
S
P
F
V
I
A
Maize
Zea mays
NP_001152032
543
61643
S533
I
E
A
P
K
G
A
S
R
R
S
R
A
K
M
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
96.5
80.1
N.A.
80.7
81.3
N.A.
N.A.
N.A.
N.A.
75.7
N.A.
N.A.
N.A.
36.7
51.1
Protein Similarity:
100
98.3
97.2
82.6
N.A.
84.4
85.3
N.A.
N.A.
N.A.
N.A.
83.7
N.A.
N.A.
N.A.
55
65.6
P-Site Identity:
100
93.3
86.6
0
N.A.
6.6
6.6
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
100
93.3
86.6
6.6
N.A.
13.3
26.6
N.A.
N.A.
N.A.
N.A.
20
N.A.
N.A.
N.A.
20
6.6
Percent
Protein Identity:
23.6
22.4
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
37.2
36.2
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
0
40
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
10
0
0
0
0
0
10
0
10
% A
% Cys:
0
0
0
10
0
0
0
10
28
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
19
19
10
0
0
0
0
% D
% Glu:
0
19
10
0
10
0
0
0
0
0
0
0
10
0
28
% E
% Phe:
0
0
0
0
10
28
0
10
0
0
0
10
0
28
28
% F
% Gly:
0
10
0
0
0
19
0
0
0
0
0
37
0
0
0
% G
% His:
0
0
0
19
28
28
28
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
10
10
0
0
0
10
10
10
% I
% Lys:
0
0
0
0
10
0
0
10
0
10
0
0
0
10
0
% K
% Leu:
0
10
19
10
19
10
0
0
0
0
0
0
0
10
0
% L
% Met:
28
10
19
28
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
0
0
0
10
19
46
0
10
0
0
% N
% Pro:
0
19
19
10
0
0
10
0
0
0
10
10
0
0
10
% P
% Gln:
0
0
0
10
0
10
0
0
10
0
0
0
0
0
0
% Q
% Arg:
19
0
0
10
10
0
19
19
19
37
0
10
0
0
0
% R
% Ser:
28
28
10
10
10
10
37
28
10
19
28
37
46
28
0
% S
% Thr:
0
10
10
0
10
0
0
0
0
0
0
0
0
0
10
% T
% Val:
10
0
10
0
0
0
0
19
0
0
0
0
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
10
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _